1-NM-PP1. Catalog No.:MC0998. 4E1rcat. Catalog No.:MC0847. 4SC-202. Catalog No.:MC0577. 4μ8C. Catalog No.:MC1332. ABT-751(E 7010). Catalog
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Arms. 40.1. Duration (Months) 1.8 NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. ABT‐751 is an oral antimitotic agent in phase 2 development. In cancer patients, ABT‐751 is extensively metabolized by glucuronidation and sulfation. To identify the UGT isoforms involved in ABT‐75 ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.
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ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively. - Mechanism of Action & Protocol.
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Schedule 1 (closed to accrual as of 5/25/2009): Patients receive oral ABT-751 once daily on days 1-7. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. ABT 751, Tocris Bioscience™ Click to view available options Quantity: 10mg 50mg This item is not returnable. View return policy.
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AFJ.751 Städning. ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.
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Patients receive oral ABT-751 once daily on days 1-7. Treatment repeats every 21 days for 52 courses in the absence of disease progression or unacceptable toxicity. Blood is collected periodically during course 1 for pharmacokinetic studies. Quality of life is assessed at baseline and prior to each course of treatment.
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